Probably not. Windows drive mappings are normally user-specific and therefore only available while a specific user is logged on. Depending on what you want to use this drive to do you may be able to get away with it but it will never work exactly the same as a disk attached to the server.
Are you using your NetApp filer as your VM datastore? If so it sounds like you would be better off creating a virtual disk for your server and migrating the data from the CIFS volume to that - this will give you all the advantages of a physical disk and NetApp storage. Alternatively you might want to use Raw Device Mapping rather than a virtual disk. As another alternative you could use iSCSI in your VM to attach to the data on the NetApp filer. None of these methods use CIFS.
CIFS is "file level" storage. To do what you want to do you will probably need "block level" storage or virtual disks. Virtual disks can be hosted on block-level storage or file-level storage but only if you use NFS, not CIFS.
SMB2 works the same as CIFS in this case. As I said, you might be able to get it to work depending on exactly what you want to achieve but it is not the "proper" way to do it. It is similar to but not the same as having a disk attached to the server.