We have been aware of this intermittent issue in our environment for about 2 years now with Microsoft Word and Microsoft Excel, ever since we switched from physical servers to the NetApp CIFS shares.
Word reports the document is already in use when it is not.
Excel reports that the file is locked by another user when it is not
I recently found a NetApp KB article mentioning similar issues:
KB article : 1011549
https://kb.netapp.com/support/index?page=content&id=1011549
Running cifs stat, it looks like we our maxing out the default multiplex value.
I have not had a chance to try a higher value yet. Hopefully soon.