You're well below the limit of 324TB, 30 shelves or 720 disks/LUNs. You should end up with ~66TB usable on each node (after root aggregagtes, spares and parity disks) across 2 (16 disk) RAID groups in the data aggregate. With VMware you'll want to be careful more with your Datastore sizes to make sure you can handle the backup/restore RPO/RTO than you will any technical limits. We try to keep our Datastores ~3TB and use Datastore Clusters to ease placement and management, but it all depends on the process and technology you plan to utilize for your backup/DR capabilities.
