If you want more space savings, you can definitely do so. If the inline efficiencies are drawing plenty of space savings then you should be fine.
Generally deduplication is more impactful on hard drives. Since you have an AFF, CPU cycles will be shared as a background task with frontend workloads. All spare CPU cycles will be used, so CPU will probably be 100% busy. This is expected as dedupe wants to finish as fast as possible.