As @parisi said - in SMB 2+ we usually don't see an impact. Just make sure the clients indeed use SMB 2+, as things like un-delegated CNAME aliases can get it to fallback to SMB1
CMD:
vserver cifs session show -vserver vserver_name -protocol-version SMB1
or PS:
Get-NcCifsSession -Controller $clustersSessions | ? {$_.ProtocolVersion -eq "smb1" -or $_.AuthMechanism -match "ntlm"} | select vserver,WindowsUser,Address,AuthMechanism,ProtocolVersion -Unique