Hello @bsnyder27,
Unfortunately not without using storage array level replication, like SnapMirror, to move the entire datastore followed by performing a cutover...which is a disruptive operation (the VMs would need to be shutdown, removed from inventory at the old location, then re-added from the new).
Did you enable (post-process) deduplication after the data was added to the volume? If so you'll need to do
volume efficiency start -vserver <vserver_name> -volume <volume_name> -scan-all
Hope that helps.
Andrew
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