I ran across this issue in 4.1. I stumbled across the solution that worked for me, The issue was on the Client side. (My workstations where the vsphere client was running from)
I found that once I removed the “Chrome frame” program which included the “chrome frame” plug-in in IE, that it solved my issue.
I reinstalled the Chrome frame program again to validate the solution and again the tab stopped working and removing it again solved the issue.
Hope that helps